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About

Xiangyu Guo is a pioneering researcher at the intersection of robotics, micro-manipulation, and biomedical engineering, with a focus on automating delicate cellular and surgical procedures. His major contributions span three key areas: robotic single-cell dissection from tissue, robot-assisted subretinal injection, and automated cell microinjection systems. Notably, his 2023 work on "Automated Dissection of Intact Single Cell From Tissue Using Robotic Micromanipulation System" (25 citations) introduced a groundbreaking framework that intelligently cuts single cells from tissue sections, bridging a critical gap in bioscience research. He also advanced ophthalmic surgery with a deep learning framework for needle detection and localization in robot-assisted subretinal injection (14 citations), enhancing precision beyond human capability. Guo's innovative designs include a microinjector with an FBG force sensor for single-cell injection (11 citations) and a novel automated system for zebrafish embryo microinjection (10 citations), the first to integrate a microfluidic chip for continuous cell transport and injection. His work on programmable magnetic microgrippers (6 citations) further demonstrates his versatility in achieving robust microscopic grasping. With a total of over 70 citations across his most-cited papers, Guo's research is shaping the future of automated microsurgery and cellular manipulation, offering transformative tools for life science and clinical applications.