Nathan McDannold

About

Nathan McDannold is a leading figure in the field of image-guided therapy, with a primary focus on the development and clinical translation of focused ultrasound (FUS) for non-invasive brain interventions. His key research areas encompass MRI-guided neurosurgery, thermal ablation, and blood-brain barrier (BBB) disruption. A major contribution is his pioneering work integrating advanced intraoperative imaging, registration, and navigation technologies at Brigham and Women's Hospital, as detailed in his highly cited 2006 paper (43 citations). He has also been instrumental in democratizing non-invasive brain stimulation by introducing open-source neuronavigation tools, such as the 3D Slicer platform, for multimodal applications including FUS. This work, published in 2019, bridges the gap between surgical navigation and emerging therapeutic ultrasound techniques. With a career spanning over two decades, McDannold’s research has enabled precise, targeted treatments for brain disorders, from tumors to neurological conditions, significantly advancing the safety and efficacy of minimally invasive neurosurgery.

Research Focus

Key Achievements

Top Papers

1. 1
   Image-guided neurosurgery at Brigham and Women's Hospital

   43 citations · 2006
2. 2
   Open-source neuronavigation for multimodal non-invasive brain\n stimulation using 3D Slicer

   6 citations · 2019

Key Collaborators

Contact & Links