Marjan Jahangiri

National Health Service, St George’s University Hospitals NHS Foundation Trust, University of London

Papers

Total Citations

597

H-Index

About

Marjan Jahangiri is a distinguished cardiothoracic surgeon and researcher whose work centers on the vascular extracellular matrix (ECM) and its role in aortic disease. Her major contributions lie in applying advanced proteomics to characterize the ECM composition of the human aorta, providing the first detailed maps of the proteins that maintain vessel wall integrity. In her landmark 2010 study (290 citations), she pioneered the proteomic profiling of extracellular space components in healthy aortas, establishing a baseline for understanding vascular pathology. Building on this, her 2011 investigation (286 citations) revealed how ECM remodeling drives abdominal aortic aneurysms (AAA), identifying novel protein changes beyond the known elastin and collagen degradation. These findings have reshaped our understanding of aneurysm pathogenesis and opened new therapeutic targets. Beyond the lab, Jahangiri is a leading voice in surgical education, evidenced by her influential 2018 paper on cardiothoracic training in the UK. Her work bridges molecular discovery and clinical practice, making her a vital figure in vascular biology and surgical innovation.