Computational biology

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

Mark Schena, Dari Shalon, Ronald W. Davis, Patrick O. Brown

Citations: 9594 • 1995

Printing Proteins as Microarrays for High-Throughput Function Determination

Gavin MacBeath, Stuart L. Schreiber

Citations: 2764 • 2000

Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

Jesse W.-H. Li, John C. Vederas

Citations: 2051 • 2009

The impact of next-generation sequencing technology on genetics

Elaine R. Mardis

Citations: 2045 • 2008

Toxicity Testing in the 21st Century: A Vision and a Strategy

Daniel Krewski, Daniel Acosta, Melvin E. Andersen, Henry A. Anderson, John C. Bailar, Kim Boekelheide, Robert J. Brent, Gail Charnley, Vivian G. Cheung, Sídney Green, Karl T. Kelsey, Nancy I. Kerkvliet, Abby A. Li, Lawrence McCray, Otto Meyer, Reid D. Patterson, William D. Pennie, Robert A. Scala, Gina Solomon, Martin L. Stephens, James D. Yager, Lauren Zeise, Staff of Committee on Toxicity Test

Citations: 1675 • 2010

Parallel human genome analysis: microarray-based expression monitoring of 1000 genes.

Mark Schena, Dari Shalon, Renu A. Heller, Anwei Chai, P O Brown, Ronald W. Davis

Citations: 1608 • 1996

A Single-Cell Transcriptome Atlas of the Human Pancreas

Mauro J. Muraro, Gitanjali Dharmadhikari, Dominic Grün, Nathalie Gröen, Tim Dielen, Erik W.L. Jansen, Léon van Gurp, Marten A. Engelse, Françoise Carlotti, Eelco J.P. de Koning, Alexander van Oudenaarden

Citations: 1505 • 2016

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

Jeremy J. Agresti, Eugene Antipov, Adam R. Abate, Keunho Ahn, Amy C. Rowat, Jean‐Christophe Baret, Manuel Márquez, Alexander M. Klibanov, Andrew D. Griffiths, David A. Weitz

Citations: 1147 • 2010

A high-throughput gene knockout procedure for <i>Neurospora</i> reveals functions for multiple transcription factors

Hildur V. Colot, Gyungsoon Park, G. Turner, Carol S. Ringelberg, Christopher M. Crew, Liubov Litvinkova, Richard L. Weiss, Katherine A. Borkovich, Jay Dunlap

Citations: 1143 • 2006

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

Ola Blixt, Tony S. Mondala, Christopher N. Scanlan, Margaret E. Huflejt, Richard Alvarez, Marian C. Bryan, Fabio Fazio, D.A. Calarese, James Stevens, Nahid Razi, David Stevens, J.J. Skehel, Irma van Die, Dennis R. Burton, Ian A. Wilson, Richard D. Cummings, Nicolai V. Bovin, Chi‐Huey Wong, James C. Paulson

Citations: 1099 • 2004

Progress with gene‐product mapping of the Mollicutes: <i>Mycoplasma genitalium</i>

Valerie C. Wasinger, Stuart J. Cordwell, Anne Poljak, Jun X. Yan, Andrew A. Gooley, Marc R. Wilkins, Mark W. Duncan, R. J. Harris, Keith L. Williams, Ian Humphery‐Smith

Citations: 946 • 1995

Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions

Brian B. Haab, Maitreya J. Dunham, Patrick O. Brown

Citations: 891 • 2001

DNA chips: State-of-the art

G. Ramsay

Citations: 789 • 1998

Distributed multirobot localization

Stergios I. Roumeliotis, George A. Bekey

Citations: 694 • 2002

Aptamers come of age – at last

David H. J. Bunka, Peter G. Stockley

Citations: 692 • 2006

Advancing Crop Transformation in the Era of Genome Editing

Fredy Altpeter, Nathan M. Springer, Laura Bartley, Ann E. Blechl, Thomas P. Brutnell, Vitaly Citovsky, Liza Conrad, Stanton B. Gelvin, David Jackson, Albert P. Kausch, Peggy G. Lemaux, June I. Medford, Martha Orozo-Cardenas, David M. Tricoli, Joyce Van Eck, Daniel F. Voytas, Virginia Walbot, Kan Wang, Zhanyuan J. Zhang, C. Neal Stewart

Citations: 688 • 2016

Autoantigen microarrays for multiplex characterization of autoantibody responses

William H. Robinson, Carla DiGennaro, Wolfgang Hueber, Brian B. Haab, Makoto Kamachi, Erik J. Dean, Sylvie Fournel, Derek A. Fong, Mark C. Genovese, Henry E. Neuman de Vegvar, Karl Skriner, David L. Hirschberg, Robert I. Morris, Sylviane Muller, Ger J.M. Pruijn, Walther J. van Venrooij, Josef S. Smolen, Patrick O. Brown, Lawrence Steinman, Paul J. Utz

Citations: 677 • 2002

Functional genomic hypothesis generation and experimentation by a robot scientist

Ross D. King, Kenneth E. Whelan, Ffion Mair Jones, Philip G. K. Reiser, Christopher H. Bryant, Stephen Muggleton, Douglas B. Kell, Stephen G. Oliver

Citations: 660 • 2004

Locating protein-coding regions in human DNA sequences by a multiple sensor-neural network approach.

Edward C. Uberbacher, Richard Mural

Citations: 658 • 1991

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

Pasi Soininen, Antti J. Kangas, Peter Würtz, Taru Tukiainen, Tuulia Tynkkynen, Reino Laatikainen, Marjo‐Riitta Järvelin, Mika Kähönen, Terho Lehtimäki, Jorma Viikari, Olli T. Raitakari, Markku J. Savolainen, Mika Ala‐Korpela

Citations: 641 • 2009