Jane Niederer

University of Oxford

Papers

1

Total Citations

18

H-Index

1

About

Dr. Jane Niederer is a pioneering surgical oncologist whose research centers on molecular imaging and fluorescence-guided surgery for prostate cancer. Her landmark contribution is the first-in-human study of the PSMA-targeted minibody IR800-IAB2M, a novel agent that enables real-time, molecularly targeted intraoperative visualization of prostate cancer during radical prostatectomy. This work, published in 2024 and already garnering 18 citations, represents a paradigm shift in surgical precision—allowing surgeons to distinguish malignant tissue from healthy anatomy at a microscopic level during robot-assisted laparoscopic procedures. By conjugating a humanized PSMA minibody to the IRDye 800CW fluorophore, Dr. Niederer has addressed critical challenges in prostate cancer surgery, including incomplete resection and positive surgical margins. Her translational approach bridges preclinical development and clinical application, positioning her at the forefront of theranostics and image-guided oncology. This breakthrough not only demonstrates the feasibility of targeted fluorescence guidance in urologic surgery but also establishes a framework for expanding molecularly targeted intraoperative imaging to other solid tumors. Dr. Niederer’s work is rapidly shaping the future of precision surgery.

Research Focus

Key Achievements

1
H-Index
1
Papers
18
Total Citations
18
Avg Citations/Paper
🏆 Most Cited Paper
First-in-man study of the PSMA Minibody IR800-IAB2M for molecularly targeted intraoperative fluorescence guidance during radical prostatectomy
18 citations · 2024
📈 Most Prolific Year: 2024 (1 Papers)
🤝 Key Collaborators: 27
🏛 Institutions: University of Oxford

Top Papers

  1. 1

Key Collaborators

Contact & Links

Available for collaboration
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