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Driven by a profound commitment to restoring independence for individuals with paralysis, Lay Keng Priscilla Lim has made pioneering contributions to the field of brain-machine interfaces (BMIs). Her research focuses on developing wireless neural systems that translate brain signals into real-world mobility. In her landmark 2016 study, cited over 55 times, Lim demonstrated that macaques with tetraplegia could achieve independent mobility by using a wireless BMI to control a robotic platform on which they sat. This work marked a critical transition from stationary cursor control to self-directed, physical movement, directly addressing a core loss for those with severe motor impairments. By integrating wireless technology, she eliminated the physical tethers that limited previous systems, paving the way for more natural and practical assistive devices. Lim’s research is a vital step toward creating closed-loop neural prosthetics that can restore not just communication, but the fundamental human ability to explore and navigate one’s environment.