Giusi Pisano

Università Cattolica del Sacro Cuore, Leiden University Medical Center

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About

Giusi Pisano is at the forefront of precision surgery, specializing in molecular image–guided interventions for gynaecological and urological cancers. Her research bridges the gap between nuclear medicine and surgical oncology, developing real-time imaging technologies that enhance tumor detection and margin assessment during operations. Her most cited work, a comprehensive 2024 review on molecular image–guided surgery in gynaecological cancer (12 citations), provides a critical overview of clinical and technological advances in the field. More recently, Pisano led a pioneering feasibility study on gantry-free hybrid hSPECT/LiDAR imaging for back-table specimen scanning during PSMA-radioguided surgery (2025, 3 citations). This innovative approach addresses the challenge of low PSMA-receptor expression and background signal that can hinder in vivo detection, offering a practical ex vivo solution to improve surgical precision. Her work has significant implications for reducing positive margins and improving patient outcomes in prostate and gynaecological cancers. Pisano’s contributions are shaping the next generation of image-guided surgical tools, making her a key figure in the evolution of molecularly targeted, data-driven operative care.