Carmine Gentile
Medical University of South Carolina, University of Technology Sydney
Papers
3
Total Citations
228
H-Index
2
About
Carmine Gentile is a pioneering researcher at the intersection of tissue engineering, bioprinting, and cardiac regeneration. His work focuses on solving the critical challenge of vascularizing engineered tissues—a key bottleneck in creating functional organ replacements. Gentile’s highly cited 2010 paper, “Towards organ printing: engineering an intra-organ branched vascular tree” (221 citations), laid foundational principles for fabricating hierarchical vascular networks within 3D-printed tissues, directly addressing the problem of nutrient delivery in thick constructs. This contribution has shaped the field of organ printing and remains a touchstone for researchers working on tissue vascularization. More recently, Gentile has advanced translational cardiac repair by designing novel surgical instruments for minimally invasive delivery of bioengineered cardiac patches. His proof-of-concept designs for robotic transplantation (2021, 2022), tested in porcine models, represent a paradigm shift—moving patch-based myocardial regeneration from open surgery toward robotically-enabled, less invasive procedures. Though these reports are early-stage, they signal a practical path to clinical application. Gentile’s work uniquely bridges fundamental biofabrication science with surgical innovation, positioning him as a key figure in the future of regenerative cardiology.
Research Focus
Key Achievements
Top Papers
- 1Towards organ printing: engineering an intra-organ branched vascular tree221 citations · 2010
- 2
- 3