Papers
17
Total Citations
376
H-Index
10
About
Shinya Sakuma is a pioneering researcher at the intersection of microrobotics, microfluidics, and cell biomechanics, whose work has fundamentally advanced our ability to quantify and understand the mechanical properties of individual biological cells. His most influential contribution — a framework for evaluating red blood cell fatigue through extensibility and recoverability metrics (112 citations) — introduced a novel paradigm for assessing erythrocyte health, with direct implications for diagnosing blood disorders and understanding circulatory physiology. Building on this foundation, Sakuma developed robot-integrated microfluidic chips ("robochips") capable of high-throughput, high-precision mechanical characterization of diverse cell types, including oocytes, single-cell spheroids, and cyanobacteria. His ultra-high-speed "Catch-Load-Launch" manipulation system revealed critical time windows for cytoskeletal remodeling in erythrocytes, while his untethered microrobot platforms enabled delicate on-chip procedures such as oocyte enucleation — tasks previously difficult to perform in confined microfluidic environments. Collectively, Sakuma's research has garnered over 340 citations, establishing him as a leading innovator in single-cell mechanical analysis and laying essential groundwork for next-generation diagnostic tools and cellular surgery technologies.
Research Focus
Key Achievements
Top Papers
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- 5On-chip enucleation of an oocyte by untethered microrobots32 citations · 2014
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