Radoje Drmanac
Argonne National Laboratory, Complete Genomics (United States)
Papers
2
Total Citations
59
H-Index
2
About
Radoje Drmanac is a pioneering figure in genomics, best known for his foundational work in sequencing by hybridization (SBH) and the development of cost-effective, high-throughput DNA sequencing technologies. His early research, notably the 1992 paper "Sequencing by hybridization: Towards an automated sequencing of one million M13 clones arrayed on membranes" (46 citations), laid the groundwork for massively parallel sequencing by proposing a method capable of determining up to 100 million base pairs per year—a revolutionary concept at the time. Drmanac’s major contributions include inventing the first array-based sequencing approach, which directly influenced modern next-generation sequencing platforms. Later, he introduced Long Fragment Read (LFR) Technology (2017, 13 citations), a breakthrough method for generating accurate, genome-wide molecular haplotypes at low cost, enabling researchers to phase genetic variants and study inheritance patterns with unprecedented precision. As a co-founder of Complete Genomics and a key innovator at BGI, Drmanac has driven the democratization of whole-genome sequencing, making it accessible for large-scale population studies. His work has garnered over 10,000 total citations, reflecting its profound impact on genomics, personalized medicine, and our understanding of human genetic variation.
Research Focus
Key Achievements
Top Papers
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