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About

Mathias Winkler is a pioneering urological surgeon and researcher whose work has fundamentally shaped the modern management of prostate cancer, from diagnosis to treatment. His key research areas include the evolution of prostate biopsy techniques, robotic-assisted surgery, and innovative approaches to intraoperative margin assessment. Dr. Winkler was instrumental in establishing the UK’s first robotic prostatectomy program in 2004, a landmark achievement documented in his highly cited early work (30 citations). He has since driven the adoption of robotic targeted MRI-US fusion prostate biopsy, demonstrating the efficacy of the centroid targeting approach in a prospective study (38 citations). His impact extends to major clinical trials, including the PACE-A phase 3 RCT (31 citations), which compared stereotactic body radiotherapy to surgery for localized prostate cancer, addressing a critical therapeutic equipoise. More recently, Dr. Winkler is leading the FLUORESCE study on fluorescence confocal microscopy for real-time margin assessment during prostatectomy, and has developed the novel LaserSAFE technique, aiming to improve surgical precision and patient outcomes. With a career spanning two decades, his work has garnered hundreds of citations, cementing his reputation as a transformative figure in urologic oncology.