Lubomir B. Smilenov

Columbia University Irving Medical Center

Papers

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About

Lubomir B. Smilenov is a leading researcher in radiation biology and DNA damage repair, with a particular focus on high-throughput technologies for assessing cellular responses to ionizing radiation. His most significant contribution is the development of the Rapid Automated Biodosimetry Tool (RABiT), a groundbreaking system that enables the high-throughput evaluation of global double-strand break (DSB) repair. This innovation, detailed in his highly cited 2014 paper (43 citations), addresses a critical need in radiation biodosimetry by allowing rapid, automated analysis of DNA repair capacity in large populations—essential for triage after radiological incidents. Smilenov’s work bridges molecular biology and engineering, providing a scalable platform for studying DSB repair kinetics and individual radiosensitivity. His research has profound implications for both clinical radiation oncology and emergency response, offering a practical tool to assess radiation exposure and repair efficiency. By advancing automated biodosimetry, Smilenov has positioned himself at the forefront of integrating high-throughput methods into radiation biology, making his work indispensable for researchers seeking to understand and quantify DNA damage responses in real-world scenarios.