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About

Lars Egevad is a prominent urological pathologist and researcher whose work has profoundly shaped our understanding of prostate cancer diagnosis, surgical outcomes, and oncological management. His research focuses primarily on robot-assisted radical prostatectomy (RARP), surgical margin assessment, and advanced preoperative imaging modalities, including multiparametric MRI and ⁶⁸Ga-PSMA PET/CT. Egevad's most influential contributions center on elucidating the clinical significance of positive surgical margins (PSMs) following RARP — work that has accumulated over 300 citations across multiple studies. His landmark investigations demonstrated how PSM size, focality, and location independently predict biochemical recurrence, providing surgeons with actionable pathological benchmarks. His long-term outcome studies, tracking patients over 10 and even 20 years, have been instrumental in validating RARP's oncological efficacy against established open surgical standards. More recently, Egevad has advanced the field of precision preoperative staging by comparing mpMRI and PSMA PET/CT against detailed histopathological analysis in large patient cohorts exceeding 1,000 men, clarifying where imaging succeeds and falls short in detecting clinically significant cancer. His contributions to the European Association of Urology Robotic Urology Section Scientific Working Group further reflect his leadership in shaping evidence-based guidelines, making his research essential reading for urologists and oncologists worldwide.