Papers
3
Total Citations
84
H-Index
3
About
Catalin Schiopu is a pioneering researcher in the field of analytical biochemistry and cancer glycomics, with a primary focus on the structural characterization of gangliosides—sialic acid-containing glycosphingolipids implicated in tumor invasion and metastasis. His major contributions center on the development and application of advanced mass spectrometry methodologies for mapping ganglioside expression in brain tumors. Notably, his 2011 study on brain metastasis of lung adenocarcinoma (48 citations) introduced a fully automated chip-nanoelectrospray mass spectrometry approach to assess ganglioside molecular structure, providing critical insights into neoplastic cell transformation. In a subsequent 2012 study (29 citations), he successfully combined high-performance thin layer chromatography with chip-based nanoelectrospray and QTOF-MS for the first structural identification of meningioma gangliosides. Schiopu also advanced top-down proteomics by integrating electron transfer dissociation with automated chip-nanoelectrospray, enabling high-throughput protein analysis without enzymatic digestion. His work has significantly impacted cancer biomarker discovery and the understanding of glycosylation changes in brain malignancies, establishing him as a key innovator in lipidomics and proteomics technologies.
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