Cancer research

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

Suping Li, Qiao Jiang, Shaoli Liu, Yinlong Zhang, Yanhua Tian, Jing Wang, Yiguo Zou, Gregory J. Anderson, Jing-Yan Han, Yung Chang, Yan Liu, Chen Zhang, Liang Chen, Guang‐Biao Zhou, Guangjun Nie, Hao Yan, Baoquan Ding, Yuliang Zhao

Citations: 1480 • 2018

Hedgehog Target Genes: Mechanisms of Carcinogenesis Induced by Aberrant Hedgehog Signaling Activation

Yuriko Katoh, Masaru Katoh

Citations: 520 • 2009

Ribosomal Protein L5 and L11 Mutations Are Associated with Cleft Palate and Abnormal Thumbs in Diamond-Blackfan Anemia Patients

Hanna T. Gazda, Mee Rie Sheen, Adrianna Vlachos, Valérie Choesmel, Marie-Françoise O’Donohue, Hal E. Schneider, Natasha Darras, Catherine Hasman, Colin A. Sieff, Peter E. Newburger, Sarah E. Ball, Edyta Niewiadomska, Michał Matysiak, Jan Maciej Zaucha, Bertil Glader, Charlotte M. Niemeyer, Joerg J Meerpohl, Eva Atsidaftos, Jeffrey M. Lipton, Pierre‐Emmanuel Gleizes, Alan H. Beggs

Citations: 417 • 2008

Selective killing of ovarian cancer cells through induction of apoptosis by nonequilibrium atmospheric pressure plasma

Sachiko Iseki, Kae Nakamura, Moemi Hayashi, Hiromasa Tanaka, Hiroki Kondo, Hiroaki Kajiyama, Hiroyuki Kano, Fumitaka Kikkawa, Masaru Hori

Citations: 314 • 2012

A cytogenetic study of 53 human gliomas

Robert B. Jenkins, David W. Kimmel, Cheryl A. Moertel, Cloann G. Schultz, Bernd W. Scheithauer, Patrick Kelly, Gordon W. Dewald

Citations: 247 • 1989

Inflammation and Extracellular Matrix Degradation Mediated by Activated Transcription Factors Nuclear Factor-κB and Activator Protein-1 in Inflammatory Acne Lesions in Vivo

Sewon Kang, Soyun Cho, Jin Ho Chung, Craig Hammerberg, Gary J. Fisher, John J. Voorhees

Citations: 237 • 2005

The oncolytic peptide LTX-315 triggers immunogenic cell death

Heng Zhou, Sabrina Forveille, Allan Sauvat, Takahiro Yamazaki, Laura Senovilla, Yuting Ma, Peng Liu, Huikang Yang, Lucillia Bezu, Kristen E. Muller, Laurence Zitvogel, Øystein Rekdal, Oliver Kepp, Guido Kroemer

Citations: 129 • 2016

Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis

Steffan Vartanian, P. Taylur, James Lee, Peter M. Haverty, Donald S. Kirkpatrick, Kebing Yu, David Stokoe

Citations: 114 • 2015

Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients

Bente Risberg, Dana W.Y. Tsui, Heather Biggs, Andrea Ruiz-Valdepenas Martin de Almagro, Sarah‐Jane Dawson, Charlotte Hodgkin, Linda Jones, Christine Parkinson, Anna Piskorz, Francesco Marass, Dineika Chandrananda, Elizabeth Moore, James Morris, Vincent Plagnol, Nitzan Rosenfeld, Carlos Caldas, James D. Brenton, Davina Gale

Citations: 109 • 2018

In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed

Flavio Bonanini, Dorota Kurek, Sara Previdi, Arnaud Nicolas, Delilah Hendriks, Sander Ruiter, Marine Meyer, Maria Clapés Cabrer, Roelof Dinkelberg, Silvia Bonilla García, Bart Kramer, Thomas Olivier, Huili Hu, Carmen López‐Iglesias, Frederik Schavemaker, Erik Walinga, Devanjali Dutta, Karla Queiroz, Karel Domanský, Bob Ronden, Jos Joore, Henriëtte L. Lanz, Peter J. Peters, Sebastiaan J. Trietsch, Hans Clevers, Paul Vulto

Citations: 108 • 2022

A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer

Erdem Bangi, Celina Ang, Peter Smibert, Andrew Uzilov, Alexander Teague, Yevgeniy Antipin, Rong Chen, Chana Hecht, Nelson Gruszczynski, Wesley J. Yon, Denis Malyshev, Denise Laspina, Isaiah Selkridge, Aye S. Moe, Chun Yee Lau, Patricia Taik, Eric Wilck, Aarti Sonia Bhardwaj, Max W. Sung, Sara Kim, Kendra Yum, Robert Sebra, Michael Donovan, Krzysztof Misiukiewicz, Eric E. Schadt, Marshall R. Posner, Ross Cagan

Citations: 107 • 2019

Magnetic‐Powered Janus Cell Robots Loaded with Oncolytic Adenovirus for Active and Targeted Virotherapy of Bladder Cancer

Zhaoqing Cong, Songsong Tang, Leiming Xie, Ming Yang, Yangyang Li, Dongdong Lu, Jiahong Li, Qingxin Yang, Qiwei Chen, Zhiqiang Zhang, Xueji Zhang

Citations: 101 • 2022

Autonomous metal-organic framework nanorobots for active mitochondria-targeted cancer therapy

Xiqi Peng, Songsong Tang, Daitian Tang, Dewang Zhou, Yangyang Li, Qiwei Chen, Fangchen Wan, Heather Lukas, Hong Han, Xueji Zhang, Wei Gao, Song Wu

Citations: 95 • 2023

Precise Control of Customized Macrophage Cell Robot for Targeted Therapy of Solid Tumors with Minimal Invasion

Yuguo Dai, Xue Bai, Lina Jia, Hongyan Sun, Yanmin Feng, Luyao Wang, Chaonan Zhang, Yuanyuan Chen, Yiming Ji, Deyuan Zhang, Huawei Chen, Lin Feng

Citations: 89 • 2021

Biohybrid microrobots locally and actively deliver drug-loaded nanoparticles to inhibit the progression of lung metastasis

Fangyu Zhang, Zhongyuan Guo, Zhengxing Li, Hao Luan, Yiyan Yu, Audrey T. Zhu, Shichao Ding, Weiwei Gao, Ronnie H. Fang, Liangfang Zhang, Joseph Wang

Citations: 84 • 2024

Cytogenetic studies of epithelial ovarian carcinoma

Robert B. Jenkins, Duane H. Bartelt, Paul G. Stalboerger, Diane L. Persons, Richard J. Dahl, Karl C. Podratz, Gary L. Keeney, Lynn C. Hartmann

Citations: 78 • 1993

IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms

Qi Wu, Ai-Ling Tian, Bei Li, Marion Leduc, Sabrina Forveille, Peter Hamley, Warren R. J. D. Galloway, Wei Xie, Peng Liu, Liwei Zhao, Shuai Zhang, Frank Madeo, Yi Tu, Oliver Kepp, Guido Kroemer

Citations: 77 • 2021

The intra-tumoral relationship between microcirculation, interstitial fluid pressure and liposome accumulation

Shawn Stapleton, Michael Milosevic, Ian F. Tannock, Christine Allen, David A. Jaffray

Citations: 74 • 2015

Tyrosine 302 in RACK1 Is Essential for Insulin-like Growth Factor-I-mediated Competitive Binding of PP2A and β1 Integrin and for Tumor Cell Proliferation and Migration

Patrick A. Kiely, George S. Baillie, Martin J. Lynch, Miles D. Houslay, Rosemary O’Connor

Citations: 72 • 2008

Androgen Receptor Expression and Cellular Proliferation During Transition from Androgen-Dependent to Recurrent Growth after Castration in the CWR22 Prostate Cancer Xenograft

Desok Kim, Christopher W. Gregory, Frank S. French, Gary J. Smith, James L. Mohler

Citations: 70 • 2002