Bonnie J. Howell
Papers
2
Total Citations
12
H-Index
2
About
Dr. Bonnie J. Howell is a leading researcher in infectious disease pharmacology, with a focus on HIV latency reversal and antibacterial drug development. Her work bridges cutting-edge automation with pharmacodynamic modeling to tackle persistent challenges in chronic infections. Dr. Howell’s major contributions include the development of novel in vitro platforms that enable high-throughput, real-time assessment of drug efficacy. Her 2021 study on HIV latency reversal used an automated system to model the pharmacokinetic/pharmacodynamic (PK/PD) profile of histone deacetylase inhibitors (HDACis), providing critical insights into eradicating latent HIV reservoirs—a key barrier to curing chronic infection. In 2022, she advanced antibacterial research by creating a fully automated platform for agar-based measurement of viable bacterial growth, significantly reducing manual labor in dynamic PK/PD studies. Both works have garnered 6 citations each, reflecting their emerging impact. Dr. Howell’s innovative integration of automation into pharmacological modeling is poised to accelerate the translation of preclinical findings into effective therapeutic strategies, making her a pivotal figure in the fight against persistent infectious diseases.
Research Focus
Key Achievements
Top Papers
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