Astrid Baege
Papers
1
Total Citations
31
H-Index
1
About
Astrid Baege’s research focuses on the molecular mechanisms of viral oncogenesis, particularly how human papillomavirus (HPV) drives cervical cancer development. Her most cited work, a 2002 study on insulin-like growth factor-binding protein 3 (IGFBP-3), revealed that HPV type 16 E6 and E7 proteins upregulate IGFBP-3 expression during keratinocyte immortalization—a key step in cervical carcinogenesis. This finding, with 31 citations, provided early insights into how HPV disrupts growth factor signaling to promote unchecked cell proliferation. Baege’s contributions have helped illuminate the interplay between viral proteins and host cellular pathways, advancing understanding of HPV’s role in cancer progression. Her work remains a reference point for researchers studying viral oncogenes and epithelial cell transformation, underscoring her impact in the field of virology and cancer biology.
Research Focus
Key Achievements
Top Papers
- 1