Allison Berger
Papers
1
Total Citations
31
H-Index
1
About
Allison Berger is a prominent molecular biologist whose research focuses on the intersection of viral oncogenesis and cellular immortalization, particularly in the context of human papillomavirus (HPV) infection and cervical cancer. Her major contributions center on understanding how HPV oncoproteins, specifically E6 and E7, manipulate host cell signaling pathways to drive malignant transformation. In her highly cited 2002 study, Berger demonstrated that expression of insulin-like growth factor-binding protein 3 (IGFBP-3) is significantly upregulated during the immortalization of cervical keratinocytes by HPV type 16 E6 and E7 proteins, revealing a critical link between viral infection and growth factor regulation. This work, which has garnered over 30 citations, provided foundational insights into the molecular mechanisms of HPV-induced carcinogenesis. Berger's research has been instrumental in elucidating the complex interplay between viral proteins and host cellular machinery, offering potential targets for therapeutic intervention. Her findings continue to inform studies on HPV-related cancers and cellular aging, making her a key figure in the field of viral oncology and cancer biology.
Research Focus
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Top Papers
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