Alexander Schramm

Essen University Hospital, Universität Ulm

Papers

2

Total Citations

56

H-Index

2

About

Alexander Schramm is a pioneering researcher whose work bridges molecular neurobiology and cutting-edge surgical robotics. His early career focused on the dynamic proteome of neurotrophin receptor signaling, where he employed two-dimensional fluorescence difference gel electrophoresis and mass spectrometry to map changes upon ligand activation of TrkA and TrkB receptors. This foundational study (42 citations) illuminated how nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) drive neuronal survival, differentiation, and apoptosis—insights critical for understanding neurodegenerative diseases and cancer. More recently, Schramm has revolutionized orthognathic surgery. In a landmark 2023 case report (14 citations), he performed the world’s first developer-independent robot-assisted laser Le Fort I osteotomy, overcoming geometric limits of conventional tools. This achievement showcases his ability to translate complex biological understanding into tangible clinical innovation. With a career spanning from proteomic discovery to robotic precision, Schramm exemplifies how interdisciplinary research can advance both fundamental science and patient care, making him a compelling figure for students interested in the future of biomedical engineering and surgical technology.

Research Focus

Key Achievements

2
H-Index
2
Papers
56
Total Citations
28
Avg Citations/Paper
🏆 Most Cited Paper
Identification of Dynamic Proteome Changes Upon Ligand Activation of Trk-Receptors Using Two-dimensional Fluorescence Difference Gel Electrophoresis and Mass Spectrometry
42 citations · 2005
📈 Most Prolific Year: 2005 (1 Papers)
🤝 Key Collaborators: 10
🏛 Institutions: Essen University Hospital, Universität Ulm

Top Papers

  1. 1
  2. 2

Key Collaborators

Contact & Links

Available for collaboration
Content generated · 14 days ago