Cytochrome P450

Related papers: 6

Top Cited Papers

Automated high throughput ADME assays for metabolic stability and cytochrome P450 inhibition profiling of combinatorial libraries

Kelly M. Jenkins, Reginald Angeles, Marianne T. Quintos, Rongda Xu, Daniel B. Kassel, Robyn A. Rourick

Citations: 87 • 2004

Design of an Escherichia coli system for whole cell mediated steroid synthesis and molecular evolution of steroid hydroxylases

Frank Hannemann, Cornelia Virus, Rita Bernhardt

Citations: 62 • 2006

A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale

Lina Schiffer, Simone Brixius‐Anderko, Anna Hobler, Frank Hannemann, Norio Kagawa, Rita Bernhardt

Citations: 35 • 2015

Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes

Jianhua Liu, Daria I. Vernikovskaya, Gary Bora, Anthony Carlo, Woodrow Burchett, Samantha Jordan, Lloyd Wei Tat Tang, Joy C. Yang, Ye Che, George Chang, Matthew D. Troutman, Li Di

Citations: 7 • 2024

Development of a Rapid and Cost Effective Assay for the Screening of Reversible Cytochrome P450 Inhibition in Parallel with Cyp3a4 Metabolism-Dependent Inhibition Using Recombinant Proteins

Serenella Zambon

Citations: 3 • 2015

Chapter 5 In vitro dmpk screening in drug discovery, role of lc-ms/ms

Inhou Chu, Amin A. Nomeir

Citations: 3 • 2005