Gareth J. Mannall
Papers
1
Total Citations
13
H-Index
1
About
Gareth J. Mannall has made significant contributions to bioprocess engineering, particularly in the optimization of protein refolding—a critical challenge in the production of therapeutic proteins. His key research areas include high-throughput screening methodologies, automated robotic platforms, and microscale process development for biologics. Mannall’s most cited work introduces a generic hierarchical screening method that leverages an automated robotic platform to systematically analyze and optimize the refolding of proteins derived from inclusion bodies. This approach addresses the historically empirical and time-consuming nature of refolding optimization, which often results in low yields of active protein. By enabling rapid, parallel experimentation at the microscale, his method accelerates process development and enhances efficiency in biomanufacturing. With 13 citations, this foundational paper has influenced subsequent advances in automated bioprocessing. Mannall’s work is notable for bridging automation and protein science, offering practical solutions to industrial bottlenecks. His achievements underscore a commitment to streamlining biotherapeutic production, making his research invaluable for students and researchers aiming to improve yield and scalability in protein engineering.
Research Focus
Key Achievements
Top Papers
- 1