John Liddell
Papers
1
Total Citations
13
H-Index
1
About
John Liddell is a bioprocess engineer whose work centers on the high-throughput optimization of protein refolding—a critical bottleneck in biopharmaceutical production. His key research areas include automated robotic platforms for microscale process development and the systematic screening of refolding conditions for proteins derived from inclusion bodies. Liddell’s major contribution is the development of a generic hierarchical screening method that leverages an automated robotic platform to rapidly identify optimal refolding conditions, dramatically reducing the time and empirical guesswork traditionally required. This approach enables parallel testing of multiple parameters—such as dilution rates, buffer composition, and additives—accelerating the transition from inclusion bodies to active protein. His most-cited paper, "A generic hierarchical screening method for the analysis of microscale refolds using an automated robotic platform" (2011, 13 citations), remains a foundational reference for researchers seeking to streamline refolding process development. Though his citation count is modest, Liddell’s work is notable for its practical impact on industrial bioprocessing, offering a scalable, reproducible framework that bridges lab-scale optimization and commercial production. His contributions continue to inform the design of automated workflows for protein recovery.
Research Focus
Key Achievements
Top Papers
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