E. Jagudin
Papers
2
Total Citations
27
H-Index
2
About
E. Jagudin is a structural biologist whose work centers on advancing crystallographic fragment screening—a powerful technique for identifying small molecular starting points in drug discovery. Based at the Helmholtz-Zentrum Berlin, Jagudin has made pivotal contributions to the development of standardized workflows and specialized tools that enable high-throughput, reproducible fragment screening using X-ray crystallography. Their most-cited publication (2021, with 18 and 9 citations across versions) details a comprehensive pipeline that integrates crystal handling, data collection, and analysis, making crystallography a more accessible and reliable method for fragment-based ligand design. This work directly addresses a critical bottleneck in early-stage drug development: the need for robust, high-resolution structural data to guide lead optimization. By streamlining the process from crystal preparation to hit identification, Jagudin’s contributions have helped accelerate the discovery of novel binding sites and chemical probes. Their research is particularly valued by structural biologists and medicinal chemists seeking to bridge the gap between protein crystallography and practical therapeutic design. Through these efforts, Jagudin has established themselves as a key figure in the practical application of synchrotron-based fragment screening.
Research Focus
Key Achievements
Top Papers
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