J. Wollenhaupt
Papers
2
Total Citations
27
H-Index
2
About
J. Wollenhaupt is a structural biologist specializing in X-ray crystallography and fragment-based drug discovery, with a particular focus on developing high-throughput workflows for crystallographic fragment screening. Their major contributions center on establishing robust, automated pipelines at the Helmholtz-Zentrum Berlin that enable efficient identification of small-molecule binding fragments for protein targets. This work is critical for accelerating early-stage drug development, as crystallographic fragment screening provides atomic-level detail on ligand-protein interactions. Their most cited publication, "Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin" (2021), has accumulated 18 citations, demonstrating its influence in the field. This paper details the integration of sample preparation, data collection, and analysis tools that streamline the screening process, making it accessible for a wider range of research groups. Wollenhaupt’s achievements include advancing the practical application of fragment screening, which is essential for designing novel therapeutics. Their work is particularly valuable for students and researchers entering structural biology, offering a clear framework for leveraging synchrotron facilities to solve complex biological problems.
Research Focus
Key Achievements
Top Papers
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