Home /Research /MOF Drug Carriers: Biodegradable Metal–Organic Framework‐Based Microrobots (MOFBOTs) (Adv. Healthcare Mater. 20/2020)
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MOF Drug Carriers: Biodegradable Metal–Organic Framework‐Based Microrobots (MOFBOTs) (Adv. Healthcare Mater. 20/2020)

Anastasia Terzopoulou, Xiaopu Wang, Xiangzhong Chen, Mario Palacios‐Corella, Carlos Franco, Javier Herrero‐Martín, Xiao‐Hua Qin, Jordi Sort, Andrew J. deMello, Bradley J. Nelson, Josep Puigmartí‐Luis, Salvador Pané

Year
2020
Citations
2
Access
Open access

Abstract

In article number 2001031 by Xiang-Zhong Chen, Josep Puigmartí-Luis, and co-workers, highly integrated MOFBOTs are developed for targeted drug delivery. Fe@ZIF-8, a magnetic MOF composite synthesized via a one-pot procedure, plays a dual role of drug carrier and motile component of the microrobot. pH-triggered degradation of the MOF and enzymatic degradation of the gelatin-based chassis result in an overall degradable system, which opens new avenues for highly integrated fully biodegradable small-scale robots.

Keywords

Materials scienceGelatinDrug deliveryBiodegradable polymerNanotechnologyMetal-organic frameworkDrugComposite numberPolymerBiomedical engineering

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