MOF Drug Carriers: Biodegradable Metal–Organic Framework‐Based Microrobots (MOFBOTs) (Adv. Healthcare Mater. 20/2020)

摘要

In article number 2001031 by Xiang-Zhong Chen, Josep Puigmartí-Luis, and co-workers, highly integrated MOFBOTs are developed for targeted drug delivery. Fe@ZIF-8, a magnetic MOF composite synthesized via a one-pot procedure, plays a dual role of drug carrier and motile component of the microrobot. pH-triggered degradation of the MOF and enzymatic degradation of the gelatin-based chassis result in an overall degradable system, which opens new avenues for highly integrated fully biodegradable small-scale robots.