OTHER
Membrane Biochips
Fang Ye, Anthony G. Frutos, Brian Webb, Yulong Hong, Ann M. Ferrie, Fang Lai, Joydeep Lahiri
- 发表年份
- 2002
- 引用次数
- 13
- 访问权限
- 开放获取
摘要
Membrane-bound proteins represent the single most important class of drug targets. This article discusses the issues surrounding fabrication of membrane–protein microarrays by conventional robotic pin printing techniques. Ligand binding selectivity and specificity to G protein-coupled receptor (GPCR) microarrays are presented. The potential applications of these arrays for drug screening are discussed.
关键词
BiochipDNA microarrayG protein-coupled receptorComputational biologyProtein microarrayMembrane proteinMembraneMicroarrayLigand (biochemistry)Biology
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