Rational design

Soft Materials by Design: Unconventional Polymer Networks Give Extreme Properties

Xuanhe Zhao, Xiaoyu Chen, Hyunwoo Yuk, Shaoting Lin, Xinyue Liu, German Alberto Parada

Citations: 1071 • 2021

Hydrogel: Diversity of Structures and Applications in Food Science

Jinlong Li, Xin Jia, Lijun Yin

Citations: 190 • 2021

Machine Learning on a Robotic Platform for the Design of Polymer–Protein Hybrids

Matthew Tamasi, Roshan Patel, Carlos H. Borca, Shashank Kosuri, Heloise Mugnier, Rahul Upadhya, N. Sanjeeva Murthy, Michael E. Webb, Adam J. Gormley

Citations: 173 • 2022

Rational Design of Self-Healing Tough Hydrogels: A Mini Review

Wenda Wang, Ravin Narain, Hongbo Zeng

Citations: 130 • 2018

Poly(<i>N</i>‐isopropylacrylamide) and Its Copolymers: A Review on Recent Advances in the Areas of Sensing and Biosensing

Anubhab Das, Anashwara Babu, Sourav Chakraborty, Joachim F. R. Van Guyse, Richard Hoogenboom, Samarendra Maji

Citations: 117 • 2024

Supramolecular Hydrogel with Orthogonally Responsive R/G/B Fluorophores Enables Multi‐Color Switchable Biomimetic Soft Skins

Hao Liu, Shuxin Wei, Huiyu Qiu, Muqing Si, Guoqing Lin, Zhenkuang Lei, Wei Lü, Lei Zhou, Tao Chen

Citations: 77 • 2021

A structure‐based strategy for discovery of small ligands binding to functionally unknown proteins: Combination of <b><i>in silico</i></b> screening and surface plasmon resonance measurements

Naoei Yoshitani, Kazuhito Satou, Kazuki Saito, Sakura Suzuki, Hideki Hatanaka, Motoaki Seki, Kazuo Shinozaki, Hiroshi Hirota, Shigeyuki Yokoyama

Citations: 64 • 2005

A skin-mimicking multifunctional hydrogel via hierarchical, reversible noncovalent interactions

Xingkui Guo, Songlin Zhang, Shubham Patel, Xiaoou Sun, You‐Liang Zhu, Zechang Wei, Rongguo Wang, Xiaodong He, Zuankai Wang, Cunjiang Yu, Swee Ching Tan

Citations: 57 • 2025

Developing DNA Nanotechnology Using Single-Molecule Fluorescence

Roman Tsukanov, Toma E. Tomov, Miran Liber, Yaron Berger, Eyal Nir

Citations: 41 • 2014

Improving the reaction mix of a Pichia pastoris cell-free system using a design of experiments approach to minimise experimental effort

Alex J. Spice, Rochelle Aw, Daniel G. Bracewell, Karen M. Polizzi

Citations: 33 • 2020

PinaColada: peptide–inhibitor ant colony ad-hoc design algorithm

Daniel Zaidman, Haim J. Wolfson

Citations: 31 • 2016

The future of metal–organic frameworks and covalent organic frameworks: rational synthesis and customized applications

Xing Han, Wenqiang Zhang, Zhijie Chen, Yan Liu, Yong Cui

Citations: 28 • 2023

The roadmap of carbon‐based single‐atom catalysts: rational design and electrochemical applications

Kaiyuan Liu, Liping Wang, Wenxing Chen, Zhiyi Sun, Huilong Geng, Yinqi Li, Ziwei Deng, Shuai Jiang, Boran Zhou, Kedi Yu, Long Wei, Xin Gao, Zhuo Chen, Huazhang Zhai, Zhengbo Chen, Yahe Wu, Dingsheng Wang, Pengwan Chen

Citations: 23 • 2025

Rational design and additive manufacturing of grain boundary-inspired, multi-architecture lattice structures

Jianxing Yang, Xiaohong Chen, Yuanxi Sun, Chen Feng, Yang Zheng, Amir A. Zadpoor, Mohammad J. Mirzaali, Long Bai

Citations: 21 • 2023

Machine Learning on a Robotic Platform for the Design of Polymer-Protein Hybrids

Matthew Tamasi, Roshan M. Patel, Carlos H. Borca, Shashank Kosuri, Heloise Mugnier, Rahul Upadhya, N. Sanjeeva Murthy, Michael A. Webb, Adam J. Gormley

Citations: 13 • 2022

Direct Visualization of Self-Mineralized Biohybrid-Triggered Apoptosis–Ferroptosis Synergistic Tumor Therapy by Cryo-Soft X-ray Tomography

Yuting Wang, Yong Guan, Zhao Wu, Gang Liu, Yangchao Tian, Li‐Jiao Tian

Citations: 11 • 2025

Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study

M.A. Argiriadi, Silvino Sousa, David Banach, D.J. Marcotte, Tao Xiang, Medha J. Tomlinson, Megan D. Demers, Christopher M. Harris, Silvia Kwak, Jennifer Hardman, Margaret Pietras, Lisa Quinn, J. Dimauro, Baofu Ni, John A. Mankovich, David W. Borhani, Robert V. Talanian, Ramkrishna Sadhukhan

Citations: 11 • 2009

Chiral design of tough spring-shaped hydrogels for smart umbrellas

Mingqi Chen, Guangjie Song, Bin Ren, Lin Cai, Mokarram Hossain, Chunyu Chang

Citations: 10 • 2023

Light-Dissipative and Reprogrammable DNA Hydrogels Enabled by Merocyanine Photoacids

Meiqing Yang, Yuanchen Dong, Chuang Li

Citations: 10 • 2023

Next-Generation Konjac Glucomannan Hydrogels: Rational Design, Convergent Applications, and Industrial Challenges

Baoping Wang, Yue Wang, Ping Cheng, Jun Han, Zhiping Fan

Citations: 8 • 2025