Sandra Bucciantini
Papers
1
Total Citations
13
H-Index
1
About
Sandra Bucciantini’s research sits at the intersection of neuroimmunology and regenerative medicine, with a primary focus on the immune response to neural transplantation in neurodegenerative diseases. Her most cited work, “Donor-Specific Anti-HLA Antibodies in Huntington’s Disease Recipients of Human Fetal Striatal Grafts” (2013, 13 citations), challenges the long-held assumption that fetal neural grafts are immunologically privileged. By demonstrating that recipients can develop donor-specific anti-HLA antibodies, Bucciantini provided critical evidence that the brain’s immune environment is not as inert as once thought, directly informing debates on the necessity of prophylactic immunosuppression in neural allotransplantation. This contribution has shaped clinical protocols for Huntington’s disease trials, where graft survival and efficacy remain paramount. While her citation count reflects a niche but highly specialized field, her work has been instrumental in bridging transplant immunology and neurology. Bucciantini’s research underscores a pivotal shift: even in the brain, immune compatibility matters, and her findings continue to guide safer, more effective strategies for cell-based therapies in neurodegenerative disorders.
Research Focus
Key Achievements
Top Papers
- 1