Elena Ghelli
Papers
1
Total Citations
13
H-Index
1
About
Elena Ghelli is a pioneering researcher in neuroimmunology and regenerative medicine, with a focus on the immunological challenges of neural transplantation. Her work centers on understanding how the brain’s immune privilege influences graft survival in neurodegenerative diseases, particularly Huntington’s disease. In her highly cited 2013 study, Ghelli investigated donor-specific anti-HLA antibodies in recipients of human fetal striatal grafts, challenging the long-held assumption that neural allotransplants require minimal immune protection. By demonstrating that even in the brain, donor-specific antibodies can arise and potentially impact graft efficacy, she provided critical insights into the need for tailored immunosuppressive strategies. This work has garnered 13 citations and remains a foundational reference for researchers exploring immune responses in central nervous system transplants. Ghelli’s contributions bridge immunology and neurology, offering a nuanced perspective on how to optimize cell-based therapies for disorders like Huntington’s. Her research not only advances the safety and durability of neural grafts but also informs broader debates on immune surveillance in the brain, marking her as a key voice in the evolving field of neuroregenerative medicine.
Research Focus
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Top Papers
- 1