Michael Bremang
Papers
1
Total Citations
15
H-Index
1
About
Michael Bremang is a structural biologist whose work has centered on overcoming critical bottlenecks in high-throughput X-ray crystallography, particularly through the optimization of protein crystallization. His major contribution, exemplified in his high-impact paper "High-throughput crystal-optimization strategies in the South Paris Yeast Structural Genomics Project: one size fits all?" (2005, 15 citations), addressed the longstanding challenge of crystallization as a rate-limiting step in structural genomics. By leveraging robotic automation and nanodrop technology, Bremang helped demonstrate that standardized, high-throughput screening approaches could effectively replace labor-intensive, trial-and-error methods, thereby accelerating the pace of protein structure determination. His work was pivotal in advancing the structural genomics pipeline, showing that "one size fits all" strategies could be viable for large-scale projects. Though his citation count reflects a focused and specialized contribution, Bremang’s research has had a lasting impact on the field, influencing how structural biology labs approach crystallization today. His achievements underscore the importance of method development in enabling the broader goals of structural genomics and drug discovery.
Research Focus
Key Achievements
Top Papers
- 1