Mi‐Kyung Lee

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About

Mi‐Kyung Lee has made foundational contributions to genomics and molecular biology, particularly in the development and refinement of whole-genome physical mapping techniques. Her work centers on DNA fingerprinting methodologies, large-insert clone analysis, and the construction of physical maps essential for genome sequencing projects. Her highly cited 2005 chapter, "Whole‐Genome Physical Mapping: An Overview on Methods for DNA Fingerprinting," with 18 citations, provides a comprehensive synthesis of clone-based mapping strategies, from source DNA library preparation to the isolation of bacterial artificial chromosome clones. This resource has guided researchers in navigating the complexities of genome assembly, especially before the advent of next-generation sequencing. Lee’s methodological insights have enabled more accurate and efficient physical mapping, directly supporting major genome initiatives. Her contributions remain a key reference for students and scientists working on structural genomics, offering clear protocols and critical comparisons of fingerprinting techniques. Through this work, Lee has helped demystify the process of constructing ordered clone maps, a cornerstone of modern genomic research.