Matthew E. Kaplan

Papers

Total Citations

H-Index

About

Matthew E. Kaplan is a leading figure in the development of high-throughput methodologies for eukaryotic genetics, with a primary focus on *Saccharomyces cerevisiae* as a model organism. His most impactful contribution, the 2017 paper "High-throughput transformation of *Saccharomyces cerevisiae* using liquid handling robots," has garnered 17 citations and revolutionized the scalability of yeast genetics. By adapting the classic lithium acetate (LiAc) transformation protocol for automated liquid handling robots, Kaplan enabled researchers to perform thousands of transformations in a single day—a critical advance for functional genomics and synthetic biology. This work has accelerated the study of conserved cell biology processes, bridging fundamental yeast research with human disease insights. Kaplan’s innovations are widely recognized for their practicality and reproducibility, making complex genetic screens accessible to laboratories worldwide. His contributions underscore a commitment to democratizing high-throughput tools, empowering researchers to tackle large-scale questions in cell biology, genetics, and biotechnology.