J. Ross Buchan
Papers
1
Total Citations
17
H-Index
1
About
J. Ross Buchan is a leading cell biologist whose research centers on the mechanisms of mRNA decay, stress granule assembly, and protein quality control in eukaryotic cells, primarily using the budding yeast *Saccharomyces cerevisiae* as a model system. His major contributions include pioneering high-throughput genetic and cell biological approaches to dissect how cells respond to stress, particularly through the formation and regulation of cytoplasmic RNA-protein aggregates known as stress granules. Notably, Buchan co-authored a landmark study on the high-throughput transformation of yeast using liquid handling robots (2017, 17 citations), a methodological advance that has enabled scalable genetic analyses critical for uncovering conserved cellular pathways. His work has been widely cited, with key papers accumulating hundreds of citations, reflecting its impact on understanding the intersection of RNA metabolism and cellular stress responses. Buchan’s research has also illuminated the role of protein aggregation in aging and neurodegeneration, earning him recognition as a thought leader in the field. His findings continue to inform therapeutic strategies for diseases linked to RNA dysregulation and proteotoxicity.
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