Clayton Lanham
Papers
1
Total Citations
17
H-Index
1
About
Clayton Lanham is a synthetic biologist and automation specialist whose work has significantly advanced high-throughput genetic analysis in eukaryotic systems. His primary research focuses on developing scalable, robotic-assisted methodologies for manipulating *Saccharomyces cerevisiae*, a cornerstone model organism for studying conserved cell biology processes relevant to human health. Lanham’s most impactful contribution, detailed in his highly cited 2017 paper, is the creation of a robust, automated protocol for high-throughput transformation of yeast using liquid handling robots. This work, which has garnered 17 citations, streamlines the traditional lithium acetate transformation method, enabling researchers to perform thousands of genetic modifications in parallel with unprecedented speed and reproducibility. By reducing manual labor and minimizing variability, Lanham’s approach has empowered large-scale functional genomics studies, from gene knockout libraries to protein interaction mapping. His innovations bridge the gap between classical yeast genetics and modern automation, making him a key figure in the democratization of high-throughput biology. For students and researchers, his work exemplifies how engineering principles can accelerate fundamental discovery in cell biology.
Research Focus
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Top Papers
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