Mario Tombini
Papers
8
Total Citations
636
H-Index
7
About
Mario Tombini is an Italian neuroscientist and clinical neurophysiologist whose research sits at the dynamic intersection of neuroprosthetics, brain-computer interfaces, and neurorehabilitation. He is perhaps best known for his landmark 2010 work on double intraneural interface implants in human amputees, which demonstrated that peripheral nerve signals could directly control a robotic hand — a breakthrough that has garnered nearly 400 citations and helped define the field of bidirectional neural prosthetics. Building on this foundation, Tombini has investigated how combined cortical EEG and peripheral nerve stump signals can synergistically improve robotic hand control, advancing both the science and clinical applicability of upper-limb prostheses. His research extends into stroke neurorehabilitation, where he has shown that robot-aided therapy induces measurable inter-hemispheric plasticity correlating with motor recovery in chronic stroke patients. More recently, Tombini has applied wearable sensor technology to Parkinson's disease, developing gyroscope-based methods for objectively quantifying bradykinesia in clinical settings. Across these domains, his work consistently bridges fundamental neurophysiology with translational clinical application, making meaningful contributions to our understanding of neural plasticity, sensorimotor integration, and the design of next-generation neural interfaces for people living with neurological conditions.
Research Focus
Key Achievements
Top Papers
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- 4Assessing bradykinesia in Parkinson's disease using gyroscope signals39 citations · 2017
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