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13
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About
Karen Ross is a leading figure in translational neuroscience, specializing in the development of advanced stereotaxic techniques for non-human primate models. Her core research focuses on the precise co-registration of multimodal imaging—including MRI, CT, and PET—to enable frameless, robotic-guided injections in the common marmoset. This work addresses a critical bottleneck in preclinical research: achieving millimeter-level accuracy for targeted drug delivery or viral vector infusions without the need for bulky stereotaxic frames. Ross’s most cited paper, "Co-registration of Imaging Modalities... to Perform Frameless Stereotaxic Robotic Injections in the Common Marmoset" (2021), has garnered 13 citations, reflecting its immediate utility in refining experimental protocols. By integrating robotic automation with clinical-grade imaging, she has significantly reduced surgical invasiveness and improved reproducibility, paving the way for more ethical and efficient studies of neurological disorders. Her contributions are particularly notable for bridging engineering and neuroscience, offering a scalable solution that other labs can adopt. Ross’s work is essential reading for researchers seeking to enhance precision in marmoset models while minimizing animal distress.
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