Justin M. Wolter
Papers
2
Total Citations
11
H-Index
2
About
Justin M. Wolter is a molecular biologist whose research centers on RNA biology, with a particular focus on microRNA (miRNA) function and gene regulation through untranslated regions (UTRs). His most recognized contribution is the development of the 3'LIFE assay — Luminescent Identification of Functional Elements in 3'UTRs — a high-throughput methodology that enables researchers to rapidly and systematically identify mRNA targets of specific miRNAs across hundreds of 3'UTR sequences simultaneously. This innovation addresses a critical bottleneck in the miRNA field, where determining functionally relevant targets has historically been labor-intensive and imprecise. The 3'LIFE platform leverages the well-established dual-luciferase reporter system, translating miRNA-mRNA binding events into measurable translational signals at scale. By enabling large-scale screening with reproducible precision, Wolter's work provides the broader research community with a powerful tool for mapping miRNA regulatory networks — knowledge essential to understanding gene expression in development and disease. His 2015 publications on this methodology have garnered citations across the RNA and genomics communities, reflecting the practical utility and influence of his technical contributions on downstream research in functional genomics and RNA therapeutics.
Research Focus
Key Achievements
Top Papers
- 1Detection of miRNA Targets in High-throughput Using the 3'LIFE Assay8 citations · 2015
- 2Detection of miRNA Targets in High-throughput Using the 3'LIFE Assay3 citations · 2015