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About

Hrishikesh Raghuram is a biomedical engineer whose research focuses on developing noninvasive robotic platforms for neonatal neurosurgery, specifically targeting intraventricular hemorrhage (IVH)—a severe complication of premature birth. His major contributions center on magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) systems designed to safely and precisely lyse blood clots within the brain’s ventricles, offering a potential alternative to invasive surgical drainage. In his most-cited work, “A robotic MR-guided high-intensity focused ultrasound platform for intraventricular hemorrhage: assessment of clot lysis efficacy in a brain phantom” (2022, 5 citations), Raghuram demonstrated the platform’s ability to effectively dissolve clots in realistic brain models. His related study, “A robotic magnetic resonance‐guided high‐intensity focused ultrasound platform for neonatal neurosurgery: Assessment of targeting accuracy and precision in a brain phantom” (2022, 4 citations), validated the system’s submillimetric targeting accuracy, a critical requirement for treating fragile neonatal brains. Together, these works establish a foundation for translating MRgHIFU from phantom studies toward clinical application, aiming to reduce the risk of posthemorrhagic hydrocephalus and long-term neurodevelopmental impairment in preterm infants. Raghuram’s research represents a promising step toward safer, image-guided, noninvasive interventions for one of neonatology’s most challenging conditions.