H. Armstrong

About

H. Armstrong is a leading figure in supramolecular chemistry, renowned for pioneering high-throughput methodologies that bridge computation and automation to accelerate molecular discovery. Their research focuses on the design and synthesis of organic cages and mechanically interlocked molecules, such as catenanes, using dynamic covalent chemistry. Armstrong’s most impactful contribution, the 2018 paper “High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis,” has garnered 215 citations and exemplifies their innovative fusion of computational screening with robotic synthesis. This work revolutionized the field by enabling the rapid exploration of vast reaction spaces, transforming supramolecular synthesis from a labor-intensive, design-driven process into a data-rich, scalable endeavor. By integrating machine learning with automated experimentation, Armstrong has unlocked access to previously inaccessible molecular topologies, significantly advancing the efficiency and scope of complex molecule assembly. Their achievements have established new paradigms for materials discovery, with implications for gas storage, separation, and catalysis, making Armstrong a pivotal figure in modern supramolecular chemistry and a model for interdisciplinary research.

Research Focus

Key Achievements

Top Papers

1. 1
   High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis

   215 citations · 2018

Key Collaborators

Contact & Links