Clare Chappell
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1
Total Citations
47
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1
About
Clare Chappell is a leading figure in stem cell biology and neurodevelopment, whose work has significantly advanced the scalable production and chemical screening of human induced pluripotent stem cell (iPSC)-derived neural cells. Her most-cited study, "Automated Large-Scale Culture and Medium-Throughput Chemical Screen for Modulators of Proliferation and Viability of Human Induced Pluripotent Stem Cell–Derived Neuroepithelial-like Stem Cells" (2012, 47 citations), pioneered a robust, automated platform for culturing neuroepithelial-like stem cells and identifying small molecules that modulate their growth and survival. This contribution provided a critical toolkit for high-throughput drug discovery and disease modeling in neuroscience, enabling researchers to efficiently probe mechanisms of neural proliferation and viability. Chappell’s work bridges the gap between basic stem cell research and translational applications, offering scalable solutions for generating consistent neural cell populations. Her achievements underscore a commitment to reproducibility and innovation in stem cell technologies, making her a key resource for scientists exploring regenerative medicine, neurotoxicology, and developmental biology.
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