Induced pluripotent stem cell

High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping

Stefan Czerniecki, Nelly M. Cruz, Jennifer L. Harder, Rajasree Menon, James Annis, Edgar A. Otto, Ramila E. Gulieva, Laura Islas, Yong Kyun Kim, Linh M. Tran, Timothy J. Martins, Jeffrey W. Pippin, Hongxia Fu, Matthias Kretzler, Stuart J. Shankland, Jonathan Himmelfarb, Randall T. Moon, Neal Paragas, Benjamin Freedman

Citations: 461 • 2018

Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells

Daniel Paull, Ana Sevilla, Hongyan Zhou, Aana Kim Hahn, Hesed Kim, Christopher Napolitano, Alexander M. Tsankov, Linshan Shang, Katie Krumholz, Premlatha Jagadeesan, Chris M. Woodard, Bruce Sun, Thierry Vilboux, Matthew Zimmer, Eliana Forero, Dorota Moroziewicz, Héctor Martínez, May Christine V. Malicdan, Keren A. Weiss, Lauren Bauer, Carmen R Dusenberry, Hannah Polus, Karla Therese L. Sy, David J. Kahler, William A. Gahl, Susan Solomon, Stephen Chang, Alexander Meissner, Kevin Eggan, Scott Noggle

Citations: 262 • 2015

A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®

Kristin M. Bircsak, Richard DeBiasio, Mark T. Miedel, Alaa Alsebahi, Ryan M. Reddinger, Anthony D. Saleh, Tongying Shun, Lawrence A. Vernetti, Albert Gough

Citations: 176 • 2021

Automated, scalable culture of human embryonic stem cells in feeder‐free conditions

Robert J. Thomas, D. N. Anderson, Amit Chandra, Nigel Smith, Lorraine Young, David Williams, Chris Denning

Citations: 161 • 2008

Robotic search for optimal cell culture in regenerative medicine

Genki N. Kanda, Taku Tsuzuki, Motoki Terada, Noriko Sakai, Naohiro Motozawa, Tomohiro Masuda, Mitsuhiro Nishida, Chihaya T Watanabe, Tatsuki Higashi, Shuhei A. Horiguchi, Taku Kudo, Motohisa Kamei, Genshiro A. Sunagawa, Kenji Matsukuma, Takeshi Sakurada, Yosuke Ozawa, Masayo Takahashi, Koichi Takahashi, Tohru Natsume

Citations: 96 • 2022

Tracking Stem Cell Differentiation in the Setting of Automated Optogenetic Stimulation

Albrecht Stroh, Hsing-Chen Tsai, Liping Wang, Feng Zhang, Jenny Kressel, Alexander M. Aravanis, Nandhini Santhanam, Karl Deisseroth, Arthur Konnerth, M. Bret Schneider

Citations: 89 • 2010

Automation of human pluripotent stem cell differentiation toward retinal pigment epithelial cells for large-scale productions

Florian Régent, Lise Morizur, Léa Lesueur, Walter Habeler, Alexandra Plancheron, Karim Ben M’Barek, Christelle Monville

Citations: 86 • 2019

Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells

Carlos A. Tristan, Pinar Ormanoglu, Jaroslav Slamecka, Claire Malley, Pei‐Hsuan Chu, Vukasin M. Jovanovic, Yeliz Gedik, Yogita Jethmalani, Charles Bonney, Elena Barnaeva, John Braisted, Sunil K. Mallanna, Dorjbal Dorjsuren, Michael J. Iannotti, Ty C. Voss, Sam Michael, Anton Simeonov, Ilyas Singeç

Citations: 68 • 2021

Bone tissue engineering of induced pluripotent stem cells cultured with macrochanneled polymer scaffold

Guang‐Zhen Jin, Tae Hyun Kim, Joong‐Hyun Kim, Jong‐Eun Won, So Young Yoo, Seong‐Jun Choi, Jung Keun Hyun, Hae‐Won Kim

Citations: 62 • 2012

Automated Cell Culture Systems and Their Applications to Human Pluripotent Stem Cell Studies

Maciej Daniszewski, Duncan E. Crombie, Rachael Henderson, Helena H. Liang, Raymond C.B. Wong, Alex W. Hewitt, Alice Pébay

Citations: 55 • 2017

Human Organ-on-a-Chip Microphysiological Systems to Model Musculoskeletal Pathologies and Accelerate Therapeutic Discovery

Raquel E. Ajalik, Rahul G. Alenchery, John S. Cognetti, Victor Z. Zhang, James L. McGrath, Benjamin L. Miller, Hani A. Awad

Citations: 48 • 2022

Scalable generation of sensory neurons from human pluripotent stem cells

Tao Deng, Vukasin M. Jovanovic, Carlos A. Tristan, Claire Weber, Pei‐Hsuan Chu, Jason Inman, Seungmi Ryu, Yogita Jethmalani, Juliana Ferreira de Sousa, Pinar Ormanoglu, Prisca Twumasi, Chaitali Sen, Jaehoon Shim, Selwyn S. Jayakar, Han-Xiong Bear Zhang, Sooyeon Jo, Weifeng Yu, Ty C. Voss, Anton Simeonov, Bruce P. Bean, Clifford J. Woolf, Ilyas Singeç

Citations: 48 • 2023

Automated Large-Scale Culture and Medium-Throughput Chemical Screen for Modulators of Proliferation and Viability of Human Induced Pluripotent Stem Cell–Derived Neuroepithelial-like Stem Cells

Donna McLaren, Thorsten Gorba, Anita Marguerie de Rotrou, G Radhakrishna Pillai, Clare Chappell, Alison Stacey, Sarah Lingard, Anna Falk, Austin Smith, Philipp Koch, Oliver Brüstle, Richard Vickers, Jon Tinsley, David J. Flanders, Paul Bello, Stewart Craig

Citations: 47 • 2012

High-throughput superhydrophobic microwell arrays for investigating multifactorial stem cell niches

Pengfei Zhang, Jianxiong Zhang, Shengtai Bian, Zhongyao Chen, Yawei Hu, Ruowen Hu, Jiaqi Li, Yichun Cheng, Xiaochen Zhang, Yiming Zhou, Xiaofang Chen, Peng Liu

Citations: 44 • 2016

The StemCellFactory: A Modular System Integration for Automated Generation and Expansion of Human Induced Pluripotent Stem Cells

Andreas Elanzew, Bastian Nießing, Daniel Langendoerfer, Oliver Rippel, Tobias Piotrowski, Friedrich Schenk, Michael Kulik, Michael Peitz, Yannik Breitkreuz, Sven Jung, Paul Wanek, Laura Stappert, Robert Schmitt, Simone Haupt, Martin Zenke, Niels König, Oliver Brüstle

Citations: 42 • 2020

International Coordination of Large-Scale Human Induced Pluripotent Stem Cell Initiatives: Wellcome Trust and ISSCR Workshops White Paper

Filipa Soares, Michael Sheldon, Mahendra S. Rao, Christine L. Mummery, Ludovic Vallier

Citations: 38 • 2014

Automating iPSC generation to enable autologous photoreceptor cell replacement therapy

Laura R. Bohrer, Nicholas E. Stone, Nathaniel K. Mullin, Andrew P. Voigt, Kristin R. Anfinson, Jessica L. Fick, Viviane Luangphakdy, Bradley Hittle, Kimerly Powell, George F. Muschler, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker

Citations: 30 • 2023

Non-immortalized human neural stem (NS) cells as a scalable platform for cellular assays

Lilian Hook, Joaquim Vives, Norma Fulton, Mathew Leveridge, Sarah Lingard, Martin D. Bootman, Anna Falk, Steven M. Pollard, Timothy E. Allsopp, Dennise D. Dalma‐Weiszhausz, Ann Tsukamoto, Nobuko Uchida, Thorsten Gorba

Citations: 23 • 2011

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System

Michael K. Conway, Michael J. Gerger, Erin E. Balay, Rachel O’Connell, Seth Hanson, Neil Daily, Tetsuro Wakatsuki

Citations: 22 • 2015

Establishment of a Robust Platform for Induced Pluripotent Stem Cell Research Using Maholo LabDroid

Miho Sasamata, Daisuke Shimojo, Hiromitsu Fuse, Yohei Nishi, Hidetoshi Sakurai, Tatsutoshi Nakahata, Yukiko Yamagishi, Haruna Sasaki-Iwaoka

Citations: 22 • 2021