Carlo Mancini Terracciano

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About

Carlo Mancini Terracciano is a leading figure in the development of next-generation radioguided surgery, with a primary focus on the intersection of nuclear medicine and robotics. His key research areas include intraoperative imaging, beta-emitting radiotracers, and the integration of novel detection probes for prostate cancer management. A major contribution is his pioneering work on the DROP-IN beta probe, a flexible device designed for robot-assisted radioguided surgery. In his highly cited 2020 study (43 citations), he demonstrated the first ex vivo evaluation of this probe using 68Ga-PSMA, a PET isotope, on prostate cancer specimens. This work represents a significant conceptual leap, combining the sensitivity of beta-emitting PET isotopes with the precision of robotic surgery, offering a potential alternative to traditional gamma-probe techniques. By enabling real-time, high-resolution detection of radiolabeled tumors, Terracciano’s innovations are paving the way for more accurate, minimally invasive cancer resections. His research not only advances surgical oncology but also bridges the gap between diagnostic imaging and therapeutic intervention, establishing him as a key innovator in the field of radioguided surgery.