Amy S. Purdon
Papers
1
Total Citations
51
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1
About
Amy S. Purdon is a leading figure in functional genomics, best known for her pioneering work in high-throughput genetic screening. Her major contribution is the development of a scalable platform for lentiviral overexpression screening of the human ORFeome, a breakthrough that enabled the systematic functional analysis of thousands of protein-coding genes. Her landmark 2011 paper describing this platform has garnered 51 citations, establishing a foundational tool for researchers exploring gene function in mammalian cells. By facilitating the transfer of open reading frames from the Mammalian Gene Collection into lentiviral vectors, Purdon’s work has accelerated the discovery of genes involved in disease pathways and cellular processes. Her achievements have made her a key resource for the functional genomics community, and her platform continues to be widely adopted for large-scale screens. Purdon’s contributions exemplify how innovative tool-building can transform biological research, empowering scientists worldwide to decode the human genome’s functional landscape.
Research Focus
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Top Papers
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