Monosaccharide

Related papers: 3

About

A monosaccharide is the most fundamental unit of carbohydrate chemistry — a simple sugar molecule that cannot be broken down further by hydrolysis. Common examples include glucose, fructose, and galactose, each defined by their carbon chain length, functional groups, and stereochemical configuration. In biochemistry and robotics-adjacent fields such as biosensing, biorobotics, and synthetic biology, monosaccharides serve as critical molecular building blocks. They form the basis of glycans and polysaccharides through glycosidic linkages, and their precise sequencing and synthesis are essential for understanding cell-surface recognition, protein glycosylation, and biomaterial design. Techniques such as glycosidase mimetics and controlled hydrolysis allow researchers to decode complex glycan structures by breaking them into identifiable monosaccharide components. In AI-driven drug discovery and bioengineering, accurate monosaccharide identification and synthesis methods enable the design of targeted therapeutics, biosensors, and functional biomaterials. Understanding monosaccharides is therefore foundational for engineers working at the intersection of chemistry, biology, and intelligent system design.

Top Cited Papers

Methods in Enzymology: O‐Glycosylation of Proteins

Jasna Peter‐Katalinić

Citations: 161 • 2005

A convenient synthesis of D-glucose-2-C-d derivatives, and of methyl 4,6-O-benzylidene-2-C-methyi-α-D-glucopyranoside

Alan H. Haines

Citations: 8 • 1977

Scope and limitations of carbohydrate hydrolysis for de novo glycan sequencing using a hydrogen peroxide/metallopeptide-based glycosidase mimetic

Tianyuan Peng, Zachary Wooke, Nicola L. B. Pohl

Citations: 4 • 2018