High-throughput screening

High-Throughput Assay of Oxygen Radical Absorbance Capacity (ORAC) Using a Multichannel Liquid Handling System Coupled with a Microplate Fluorescence Reader in 96-Well Format

Dejian Huang, Boxin Ou, Maureen Hampsch‐Woodill, Judith A. Flanagan, Ronald L. Prior

Citations: 1548 • 2002

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

Jeremy J. Agresti, Eugene Antipov, Adam R. Abate, Keunho Ahn, Amy C. Rowat, Jean‐Christophe Baret, Manuel Márquez, Alexander M. Klibanov, Andrew D. Griffiths, David A. Weitz

Citations: 1147 • 2010

Antibody arrays for high-throughput screening of antibody–antigen interactions

Ruud M. T. de Wildt, Chris R. Mundy, B.D. Gorick, Ian M. Tomlinson

Citations: 627 • 2000

Adaptation of High-Throughput Screening in Drug Discovery—Toxicological Screening Tests

Paweł Szymański, Magdalena Markowicz-Piasecka, Elżbieta Mikiciuk‐Olasik

Citations: 439 • 2011

High-throughput, quantitative analyses of genetic interactions in E. coli

Athanasios Typas, Robert J. Nichols, Deborah A. Siegele, Michael Shales, Sean R. Collins, Bentley Lim, Hannes Braberg, Natsuko Yamamoto, Rikiya Takeuchi, Barry L. Wanner, Hirotada Mori, Jonathan S. Weissman, Nevan J. Krogan, Carol A. Gross

Citations: 246 • 2008

Coherent membrane supports for parallel microsynthesis and screening of bioactive peptides

Holger Wenschuh, Rudolf Volkmer, Margit Schmidt, Marco Schulz, Jens Schneider‐Mergener, Ulrich Reineke

Citations: 199 • 2000

A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®

Kristin M. Bircsak, Richard DeBiasio, Mark T. Miedel, Alaa Alsebahi, Ryan M. Reddinger, Anthony D. Saleh, Tongying Shun, Lawrence A. Vernetti, Albert Gough

Citations: 176 • 2021

A Robotic Platform for Quantitative High-Throughput Screening

Sam Michael, Douglas S. Auld, Carleen Klumpp, Ajit Jadhav, Wei Zheng, Natasha Thorne, Christopher P. Austin, James Inglese, Anton Simeonov

Citations: 157 • 2008

Robo-Lector – a novel platform for automated high-throughput cultivations in microtiter plates with high information content

Robert Huber, Daniel Ritter, Till Hering, Anne-Kathrin Hillmer, Frank Kensy, Carsten H. G. Müller, Le Wang, Jochen Büchs

Citations: 147 • 2009

Optimization of a Higher Throughput Microsomal Stability Screening Assay for Profiling Drug Discovery Candidates

Li Di, Edward H. Kerns, Yan Hong, Teresa Kleintop, Oliver J. McConnell, Donna M. Huryn

Citations: 137 • 2003

A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity

Michael A. Parniak, Kyung‐Lyum Min, Scott R. Budihas, Stuart F.J. Le Grice, John A. Beutler

Citations: 128 • 2003

Towards automated production and drug sensitivity testing using scaffold‐free spherical tumor microtissues

Maren Drewitz, Marianne M. Helbling, Nicole Fried, Manuela Bieri, Wolfgang Moritz, Jan Lichtenberg, Jens M. Kelm

Citations: 124 • 2011

Droplet control technologies for microfluidic high throughput screening (μHTS)

Muhsincan Şeşen, Tuncay Alan, Adrian Neild

Citations: 117 • 2017

Novel micro‐bioreactor high throughput technology for cell culture process development: Reproducibility and scalability assessment of fed‐batch CHO cultures

Ashraf Amanullah, José M. Otero, Mark Mikola, Amy Hsu, Jinyou Zhang, John Auniņš, H. Brett Schreyer, James A. Hope, Adele Russo

Citations: 110 • 2010

Immobilized metal-affinity chromatography protein-recovery screening is predictive of crystallographic structure success

Ryan Choi, Angela Kelley, D.J. Leibly, Stephen N. Hewitt, Alberto J. Napuli, Wesley Van Voorhis

Citations: 103 • 2011

Fully automatized high‐throughput enzyme library screening using a robotic platform

Mark Dörr, Michael P. C. Fibinger, Daniel Last, Sandy Schmidt, Javier Santos‐Aberturas, Dominique Böttcher, Anke Hummel, Clare Vickers, Moritz Voß, Uwe T. Bornscheuer

Citations: 102 • 2016

First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass

Guangliang Wang, Surendra K. Rajpurohit, Fabien Delaspre, Steven L. Walker, David T. White, Alexis M. Ceasrine, Rejji Kuruvilla, Ruo‐Jing Li, Joong Sup Shim, Jun O. Liu, Michael Parsons, Jeff S. Mumm

Citations: 100 • 2015

High Throughput Screening of Physicochemical Properties and In Vitro ADME Profiling in Drug Discovery

Hong Wan, Anders Holmén

Citations: 97 • 2009

A GC-based method for high-throughput screening of enantioselective catalysts

Manfred T. Reetz, Klaus M. Kühling, Stephanie Wilensek, H. Husmann, Ulrich W. Häusig, Marcus Hermes

Citations: 96 • 2001

Micro-scaffold array chip for upgrading cell-based high-throughput drug testing to 3D using benchtop equipment

Xiaokang Li, Xinyong Zhang, Shan Zhao, Jingyu Wang, Gang Liu, Yanan Du

Citations: 94 • 2013