Lori Patnaude

Boehringer Ingelheim (Germany), Boehringer Ingelheim (United States)

Papers

Total Citations

H-Index

About

Dr. Lori Patnaude is a leading expert in assay optimization and the application of statistical design of experiments (DoE) to high-throughput screening (HTS). Her seminal work, "Assay Optimization: A Statistical Design of Experiments Approach," published in 2006 and 2007, has collectively garnered over 65 citations, establishing her as a key figure in streamlining drug discovery workflows. Dr. Patnaude’s major contribution lies in demonstrating how recent advances in robotic liquid handling can be leveraged to reduce assay optimization timelines through statistically rigorous experimental designs. By addressing the critical bottleneck created by the transition from manual to robotic HTS, her research has empowered laboratories to achieve more robust, reproducible, and efficient assays. Her work is particularly notable for bridging the gap between complex statistical theory and practical laboratory application, making DoE accessible to bench scientists. Dr. Patnaude’s insights continue to influence best practices in pharmaceutical and biotechnology settings, where rapid, reliable assay development is essential for accelerating the discovery of new therapeutics. Her legacy is one of transforming a time-consuming process into a data-driven, streamlined operation.