Jeroen Krijgsveld

Papers

Total Citations

322

H-Index

About

Jeroen Krijgsveld is a prominent researcher in the field of clinical proteomics, with a particular focus on developing innovative and efficient sample preparation workflows for protein analysis. His work has been instrumental in advancing high-throughput methodologies that enable standardized processing of diverse biological samples, including fresh-frozen tissue, formalin-fixed paraffin-embedded (FFPE) tissue, and blood. Krijgsveld's most significant contribution lies in the implementation and automation of single-pot solid-phase-enhanced sample preparation, known as SP3, a technique that has transformed low-input clinical proteomics by dramatically reducing sample requirements while maintaining analytical rigor. His 2020 publication on automated SP3 workflows has garnered an impressive 295 citations, underscoring the widespread adoption of this methodology across the research community. An earlier iteration of this work, published in 2019, further demonstrates his sustained commitment to refining and disseminating these approaches. By streamlining proteomics workflows, Krijgsveld has made large-scale, reproducible protein analysis more accessible to clinical researchers, opening new avenues for biomarker discovery and disease characterization. His research bridges the gap between cutting-edge mass spectrometry technology and practical clinical applications, making him a key figure in translational proteomics today.