Hagen von Briesen
Papers
3
Total Citations
73
H-Index
3
About
Hagen von Briesen’s research sits at the critical intersection of cryobiology and clinical immunology, with a focus on developing standardized, automated systems for cell-based therapies and vaccine evaluation. His major contributions center on solving two fundamental challenges: preserving the viability and functionality of immune cells after cryopreservation, and creating reproducible, high-throughput assays for monitoring immune responses. His landmark 2016 paper, “Toward Optimal Cryopreservation and Storage for Achievement of High Cell Recovery and Maintenance of Cell Viability and T Cell Functionality” (46 citations), established protocols that are now foundational for cell therapy manufacturing and clinical trials requiring long-term cell storage. In parallel, his work on automated HIV-1 Env-pseudotyped virus production (20 citations) directly supports global vaccine trials by enabling standardized, high-volume neutralization assays. His most recent contribution, an automated ELISpot assay (7 citations), addresses the critical need for operator safety and inter-laboratory reproducibility in T cell monitoring. Together, these achievements demonstrate von Briesen’s commitment to bridging the gap between bench research and clinical application, ensuring that cell-based immunotherapies and vaccine evaluations are both scalable and reliable.
Research Focus
Key Achievements
Top Papers
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