Erin Murphy
Papers
2
Total Citations
12
H-Index
2
About
Erin Murphy is a molecular biologist and genomics researcher whose work focuses on advancing CRISPR-based technologies for large-scale functional genomics. Her research centers on optimizing genome-wide loss-of-function screening platforms, with a particular emphasis on improving upon the limitations of conventional CRISPR-Cas9 library approaches. Murphy's most notable contribution lies in her development and refinement of CRISPR screening methodologies using AsCas12a paired with multi-guide arrays — an innovative strategy designed to enhance the efficiency, accuracy, and coverage of genome-wide screens. This work, published across 2022 and 2023 and accumulating 12 citations, addresses critical technical bottlenecks that have historically constrained the discovery power of CRISPR screens. By enabling more robust identification of novel gene functions across diverse physiological and pathophysiological systems, her contributions have meaningful implications for fields ranging from cancer biology to rare disease research. Murphy's work represents an important step toward making genome-wide CRISPR screening more reliable and accessible, positioning her as an emerging voice in the functional genomics community with growing influence among researchers designing next-generation screening libraries.
Research Focus
Key Achievements
Top Papers
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